January 5, 2026 Allan Marshall Chief Executive Officer Upexi, Inc. 3030 North Rocky Point Drive Suite 420 Tampa, FL 33607 Re: Upexi, Inc. Registration Statement on Form S-3 Filed December 22, 2025 File No. 333-292366 Dear Allan Marshall: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Lulu Cheng at 202-551-3811 with any questions. Sincerely, Division of Corporation Finance Office of Crypto Assets cc: Peter Campitiello